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Caesium chloride12/4/2023 These claims are not supported by scientific evidence. DNA fragments with differing A-T or G-C content).Ĭaesium chloride (non-radioactive) is also promoted as an alternative cancer therapy. This allows separation of DNA of different densities (e.g. At this point, the DNA will stop migrating. ![]() When DNA is centrifuged in this solution, fragments of DNA will migrate down the tube until they reach a zone where the density of the DNA is equal to the density of the solution. In this method, a caesium chloride solution is centrifuged, allowing centrifugal and diffusive forces to establish a concentration gradient (and thus a density gradient) within the centrifuge tube. The principle of the method specified is adding a caesium chloride solution to the sample as an ionization suppressant, aspirating the sample directly into. See the Goiânia accident for further details.Ĭaesium chloride is also widely used in the centrifugation of DNA, in a technique known as isopycnic centrifugation. In Brazil, such a source was stolen by scrap metal workers from a disused radiotherapy clinic, and serious injuries and deaths occurred as a result of external gamma exposure and internal exposure (the source was smashed open, releasing the water soluble caesium chloride). It is normal to use a thimble-shaped can of radioactive caesium chloride to provide the active source in a teletherapy type radiotherapy unit. As a result it is not possible with any of the insoluble caesium compounds to create the source. But for teletherapy sources, the radioactive density (Ci in a given volume) needs to be very high. For instance, radiothermal generators (RTGs) often use strontium titanate because it is insoluble in water. In the production of radioactive sources it is normal to choose a chemical form of the radioisotope which will not be dispersed with ease in the environment as a result of an accident where the source is smashed open. Radioisotopes of caesium chloride are used in nuclear medicine, including treatment of cancer. If the two atom types are similar in size (imagine field hockey balls packed with tennis balls) then in the cubic lattice the structure will be like that of sodium chloride.Ĭaesium chloride is used in the preparation of electrically conducting glasses. It is the case that in a cubic 1:1 solid where one atom type is much larger than the other that the caesium chloride type lattice is obtained, it can be thought of as a combination of basketballs and golf balls packed in a cubic manner with the golf balls in the gaps between the basketballs. ![]() The caesium chloride structure is composed of interlocking simple cubic lattices of anions and cations.
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